Questions About Ozempic®
Ozempic® injection 0.5 mg or 1 mg is an injectable prescription medicine for adults with type 2 diabetes used along with diet and exercise to improve blood sugar. It also reduces the risk of major cardiovascular events such as heart attack, stroke, or death in adults with type 2 diabetes and known heart disease.
In a 1-year study with Ozempic®, a majority of adults with an average starting A1C of 8.1% lowered their blood sugar and reached an A1C of less than 7% and maintained it.a
Average A1C reduction:
- 1.5% with 1 mg Ozempic®a
- 1.3% with 0.5 mg Ozempic®a
- 0.7% with 100 mg Januvia®a
People who reached an A1C of less than 7%:
- 73% of people taking 1 mg Ozempic®a
- 66% of people taking 0.5 mg Ozempic®a
- 40% of people taking 100 mg Januvia®a
aIn a large 1-year study of 1231 adults with an average starting A1C of 8.1% when Ozempic® or Januvia® was added to one or more diabetes pills. Individual results may vary.
- It is not known if Ozempic® can be used in people who have had pancreatitis.
- Ozempic® is not a substitute for insulin and is not for use in people with type 1 diabetes or people with diabetic ketoacidosis.
- It is not known if Ozempic® is safe and effective for use in children under 18 years of age.
Ozempic® is not a weight-loss drug. It is a medicine for adults with type 2 diabetes that, along with staying active and eating healthy, may improve blood sugar. In a 1-year study, adults with an average starting weight of 197 pounds lost around:
- 9 pounds on the 0.5 mg dose of Ozempic®b
- 12 pounds on the 1 mg dose of Ozempic®b
- 4 pounds on the 100 mg dose of Januvia®b
bResults are from a 56-week medical study with 1231 adults with type 2 diabetes which compared Ozempic® with the leading branded pill, Januvia®, when both were added to one or more diabetes pills. While many people in clinical trials lost weight, some did gain weight.
Noninsulin Ozempic® works with your body’s own ability to lower blood sugar and A1C. It helps your body release its own insulin. Ozempic® is designed to respond when your blood sugar rises.
The main ingredient in Ozempic® is called semaglutide, a man-made version of the human GLP-1 molecule, with some changes. These changes result in differences in how semaglutide acts and how long it stays in the body.