Questions About Ozempic®
Ozempic® injection 0.5 mg or 1 mg is an injectable prescription medicine for adults with type 2 diabetes that along with diet and exercise may improve blood sugar.
In a 1-year study with Ozempic®, a majority of adults with an average starting A1C of 8.1% lowered their blood sugar and reached an A1C of less than 7% and maintained it.a
Average A1C reduction:
- 1.5% with 1 mg Ozempic®a
- 1.3% with 0.5 mg Ozempic®a
- 0.7% with 100 mg Januvia®a
People who reached an A1C of less than 7%:
- 73% of people taking 1 mg Ozempic®a
- 66% of people taking 0.5 mg Ozempic®a
- 40% of people taking 100 mg Januvia®a
aIn a large 1-year study of 1231 adults with an average starting A1C of 8.1% when Ozempic® or Januvia® was added to one or more diabetes pills. Individual results may vary.
- Ozempic® is not recommended as the first choice of medicine for treating diabetes.
- It is not known if Ozempic® can be used in people who have had pancreatitis.
- Ozempic® is not a substitute for insulin and is not for use in people with type 1 diabetes or people with diabetic ketoacidosis.
- It is not known if Ozempic® is safe and effective for use in children under 18 years of age.
Non-insulin Ozempic® works with your body’s own ability to lower blood sugar and A1C. It helps your body release its own insulin. Ozempic® is designed to respond when your blood sugar rises.
The main ingredient in Ozempic® is called semaglutide, a man-made version of the human GLP-1 molecule, with some changes. These changes result in differences in how semaglutide acts and how long it stays in the body.
A 2-year safety study found that Ozempic® does not increase the risk of major cardiovascular events such as heart attack, stroke, or death.c
cBased on a medical study lasting 2 years where 3297 adults with type 2 diabetes who had a high risk of cardiovascular events and were taking their usual cardiovascular medications were also treated once weekly with either a placebo, or 0.5 mg or 1 mg doses of Ozempic®.