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Ozempic® vs Other
Type 2 Diabetes Medicines

Ozempic® lowers blood sugar and A1C

Ozempic® has been proven to significantly lower blood sugar and A1C. See how it compared to these other medicines in head-to-head studies.

Ozempic<sup>®</sup> vs Trulicity<sup>®</sup>
Ozempic® vs Trulicity®
Ozempic® vs Bydureon®
Ozempic® vs Januvia®
Ozempic® vs Lantus®

Ozempic® lowered A1C better

A 40-week study compared Ozempic® 0.5 mg with Trulicity® 0.75 mg and Ozempic® 1 mg with Trulicity® 1.5 mg in 1201 adults with type 2 diabetes who were taking metformin.

Average change in A1C

Chart 2
Chart 3

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

In the same study, Ozempic® helped more people reach an A1C goal of less than 7%.

51%

of people with a starting A1C of 8.2% who took 0.75 mg Trulicity® lowered their A1C below 7%

VS

65%

of people with a starting A1C of 8.3% who took 0.5 mg Ozempic® lowered their A1C below 7%

63%

of people with a starting A1C of 8.2% who took 1.5 mg Trulicity® lowered their A1C below 7%

VS

73%

of people with a starting A1C of 8.2% who took 1 mg Ozempic® lowered their A1C below 7%

Ozempic® lowered A1C better

A 56-week study compared Ozempic® 1 mg with Bydureon® 2 mg in 813 adults with type 2 diabetes, in combination with metformin or metformin with sulfonylurea.

Average change in A1C

Chart 7

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

In the same study, Ozempic® helped more people reach an A1C goal of less than 7%.

40%

of people with a starting A1C of 8.3% who took Bydureon® 2 mg lowered their A1C below 7%

VS

62%

of people with a starting A1C of 8.4% who took Ozempic® 1 mg lowered their A1C below 7%

Ozempic® lowered A1C better

A 56-week study compared Ozempic® 0.5 mg and 1 mg with Januvia® 100 mg in 1231 adults with type 2 diabetes when both were added to one or more diabetes pills.

Average change in A1C

Chart 9

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

In the same study, Ozempic® helped more people reach an A1C goal of less than 7%.

40%

of people with a starting A1C of 8.2% who took Januvia® 100 mg lowered their A1C below 7%

VS

66%

of people with a starting A1C of 8.0% who took Ozempic® 0.5 mg lowered their A1C below 7%

73%

of people with a starting A1C of 8.0% who took Ozempic® 1 mg lowered their A1C below 7%

Greater A1C lowering than dose–adjusted Lantus®a

A 30-week study compared Ozempic® 0.5 mg and 1 mg with Lantus® in 1089 adults with type 2 diabetes when both were added to one or more diabetes pills.

aAt the end of the study, 26% of patients on Lantus® had their dose adjusted to their blood sugar goal (or target) by a health care provider. The average daily dose of Lantus® was 29 units per day by the end of the study.

Average change in A1C

Chart 11

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

In the same study, Ozempic® helped more people reach an A1C goal of less than 7%.

40%

of people with a starting A1C of 8.1% who took Lantus® lowered their A1C below 7%

VS

55%

of people with a starting A1C of 8.1% who took Ozempic® 0.5 mg lowered their A1C below 7%

66%

of people with a starting A1C of 8.2% who took Ozempic® 1 mg lowered their A1C below 7%

Ozempic® is not for weight loss

Ozempic® was shown to help people lose more weight than these type 2 diabetes medicines.

Ozempic® is not a weight-loss drug. It is a medicine for adults with type 2 diabetes that, along with diet and exercise, may improve blood sugar.

Ozempic<sup>®</sup> vs Trulicity<sup>®</sup>
Ozempic® vs Trulicity®
Ozempic® vs Bydureon®
Ozempic® vs Januvia®
Ozempic® vs Lantus®

People lost more than double the weight on Ozempic® vs Trulicity®

Results are from a 40-week study that compared Ozempic® 0.5 mg with Trulicity® 0.75 mg and Ozempic® 1 mg with Trulicity® 1.5 mg in 1201 adults with type 2 diabetes who were taking metformin. While many people in clinical trials lost weight, some did gain weight. Ozempic® is not a weight loss drug.

Average
starting weight

Chart 5
Chart 6

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

Ozempic® helped people lose more weight vs Bydureon®

Results are from a 56-week study that compared Ozempic® 1 mg with Bydureon® 2 mg in 813 adults with type 2 diabetes in combination with metformin or metformin and sulfonylurea. While many people in clinical trials lost weight, some did gain weight. Ozempic® is not a weight loss drug.

Chart 8

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

Ozempic® helped people lose more weight vs Januvia®

Results are from a 56-week medical study with 1231 adults with type 2 diabetes which compared Ozempic® with the leading branded pill, Januvia®, when both were added to one or more diabetes pills. While many people in clinical trials lost weight, some did gain weight. Ozempic® is not a weight loss drug.

 

Chart 10

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

People lost more weight with Ozempic® vs Lantus®

Results are from a 30-week study that compared Ozempic® 0.5 mg and 1 mg with Lantus® in 1089 adults with type 2 diabetes. While many people in clinical trials lost weight, some did gain weight. Ozempic® is not a weight loss drug.

Chart 12

The most common side effects of Ozempic® may include nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation.

Are you struggling to lower your A1C goal with insulin alone?

In a randomized 40-week study of 1201 adult patients with type 2 diabetes, Ozempic® was proven to help people with type 2 diabetes lower their A1C when added to a treatment plan that included taking insulin.

Chart 4

Ozempic® may cause serious side effects, including low blood sugar (hypoglycemia). Your risk for getting low blood sugar may be higher if you use Ozempic® with another medicine that can cause low blood sugar, such as a sulfonylurea or insulin. Signs and symptoms of low blood sugar may include: dizziness or lightheadedness, blurred vision, anxiety, irritability or mood changes, sweating, slurred speech, hunger, confusion or drowsiness, shakiness, weakness, headache, fast heartbeat, and feeling jittery.

Questions for doctor

Looking to get back in your type 2 diabetes zone?

Talk to your health care provider to see if once-weekly Ozempic® is right for you. Download a discussion guide to help get you started.

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