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Dosing for Ozempic® (semaglutide) Injection

A once-weekly dosing schedule

Ozempic® is taken once a week, exactly as prescribed by your health care provider, along with diet and exercise, to lower blood sugar in adults with type 2 diabetes.

Getting started

Ozempic® pen 0.25 mg or 0.5 mg

The beginning dose is 0.25 mg once a week for the first 4 weeks. This will help give your body a chance to get used to the medicine. 

At Week 5, your health care provider will increase the dose to 0.5 mg once a week.

Additional control

Ozempic® (semaglutide) 1mg pen
Additional 1mg dosage information
Ozempic® (semaglutide) 2mg pen
Additional 2mg dosage information

Your A1C needs may shift as your type 2 diabetes changes. That’s why Ozempic® offers pens that deliver doses of 1 mg or doses of 2 mg to give you additional A1C control. And while your dose may change, nothing will change about how you take Ozempic®—the 1 mg and 2 mg dose pens are the same as the pen you already use.

The maximum dose of Ozempic® is 2 mg once a week. Always follow your health care provider's instructions on how to dose Ozempic®.

Taking Ozempic®


Take Ozempic® once a week, on the same day every week, exactly as prescribed by your health care provider. 

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You can take Ozempic® with or without food.

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You may change the day of the week you use Ozempic® as long as your last dose was taken 2 or more days before.

Your once-weekly routine with Ozempic®

Learn the key steps to using your Ozempic® pen and how you can make taking Ozempic® a part of your weekly routine.

Your health care provider should show you how to take Ozempic® before you use it for the first time.

For more information about Ozempic® pen, see the Medication Guide and Instructions for Use or talk to your health care provider.

Missed a dose?

  • If you miss a dose of Ozempic®, take the missed dose as soon as possible within 5 days after the missed dose
  • If more than 5 days have passed, skip the missed dose, and take your next dose on your regularly scheduled day
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Have questions about Ozempic®?

Call 1-866-696-4090 Monday through Friday, 9:00 am to 6:00 pm ET, to get live one-on-one support from a Diabetes Health Coach.

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Questions for your follow-up visit

Download this discussion guide to help you get the most out of a conversation with your health care provider about Ozempic® at your next visit.

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