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Ozempic® Support Programs

The Ozempic® Pen

Using your Ozempic® pen

When taken as directed, once-weekly Ozempic®, along with diet and exercise, may help lower blood sugar for adults with type 2 diabetes.

Call with questions

Have questions about Ozempic®?
Call 1-866-696-4090 Monday through Friday, 9:00 am to 6:00 pm ET, to get live one-on-one support from a Diabetes Health Coach.

Pen instructions

For more details about how to use your Ozempic® pen, view illustrated step-by-step instructions.

Learn More

If you’re used to taking a diabetes pill, you may have concerns about starting injections. Many people do. So it may help to know that the non-insulin Ozempic® pen comes with NovoFine® Plus 32G 4 mm needles—the shortest and thinnest needle available from Novo Nordisk. It’s as thin as 2 human hairs!

NovoFine® Plus 32G 4 mm needles

How do I use my Ozempic® pen?

This is a Quick Guide. 

Read the Instructions for Use and Important Safety Information before using the pen.


Quick Guide Image 1

Prepare your pen

Check your Ozempic® pen
Read the label to check that your pen contains Ozempic®. Make sure that the Ozempic® medicine in your pen is clear and colorless.


Quick Guide Image 2

Attach a new needle
Tear off the paper tab. Push and turn the needle on until it is tight. Pull off both needle caps.


Quick Guide Image 3

Check the Ozempic® flow with each new pen
Turn the dose selector until the dose counter shows the flow check symbol. Press and hold in the dose button until the dose counter shows 0. Make sure a drop appears at the needle tip. 


Quick Guide Image 4

Give your injection

Select your dose
Turn the dose selector until the dose counter shows the dose you need to inject (0.25 mg or 0.5 mg for the red‑label pen, 1 mg for the blue‑label pen).


Quick Guide Image 5

Inject your dose
Insert the needle into your skin. Press and hold down the dose button. After the dose counter reaches 0, slowly count to 6. Remove the needle from your skin.


Quick Guide Image 6

After your injection
Carefully remove the needle and place it in a sharps container. Put the pen cap back on the pen.

Where to inject
  • Using the pen, Ozempic® is injected under the skin of your abdomen, thigh, or upper arm. Do not inject into a muscle or vein.
  • Change (rotate) your injection site with each injection. Do not use the same site for each injection. If you choose to inject in the same area, always use a different spot in that area.
Missed A Dose

Your health care provider should show you how to take Ozempic® before you use it for the first time.

For more information about Ozempic® pen, see the Medication Guide and Instructions for Use or talk to your health care provider.

Missed a dose?

  • If you miss a dose of Ozempic®, take the missed dose as soon as possible within 5 days after the missed dose
  • If more than 5 days have passed, skip the missed dose, and take your next dose on your regularly scheduled day

How to store your Ozempic® pen

How to store unused pens

Store your new, unused Ozempic® pens in the refrigerator between 36°F to 46°F (2°C to 8°C).

How to store pens in use

Store your pen in use for 56 days at room temperature between 59ºF to 86ºF (15ºC to 30ºC) or in a refrigerator between 36°F to 46°F (2°C to 8°C).

Sharps disposal container

The Ozempic® pen you are using should be disposed of (thrown away) after 56 days, even if it still has Ozempic® left in it. Write the disposal date on your calendar.

Put your used Ozempic® pen and needle in an FDA-cleared sharps disposal container right away after use.

  • If you do not have an FDA-cleared sharps disposal container, you may use a household container that is:
    • made of a heavy-duty plastic
    • can be closed with a tight-fitting, puncture-resistant lid, without sharps being able to come out
    • upright and stable during use
    • leak resistant
    • properly labeled to warn of hazardous waste inside the container
Expiration date

Unused Ozempic® pens may be used until the expiration date (“EXP”) printed on the label, if kept in the refrigerator.

Do not freeze

Do not freeze Ozempic®. Do not use Ozempic® if it has been frozen.

Storage too hot

Keep Ozempic® away from heat and out of the light.

Storage too cool

When stored in the refrigerator, do not store Ozempic® pens directly next to the cooling element.

Keep out of reach of children

Keep Ozempic® and all medicines out of the reach of children.

Pen with cap

Keep the pen cap on when not in use.